![BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance](https://www.life-science-alliance.org/content/lsa/1/1/e201800026/F3.large.jpg)
BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance
![BACE2, as a novel APP θ‐secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome - Sun - 2006 - The FASEB Journal - Wiley Online Library BACE2, as a novel APP θ‐secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome - Sun - 2006 - The FASEB Journal - Wiley Online Library](https://faseb.onlinelibrary.wiley.com/cms/asset/455b5f28-b55d-4080-91b9-7a3938ff8c5b/fsb2fj055632com-fig-0005-m.jpg)
BACE2, as a novel APP θ‐secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome - Sun - 2006 - The FASEB Journal - Wiley Online Library
Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2 | Journal of Medicinal Chemistry
![BACE2 variant identified from HSCR patient causes AD-like phenotypes in hPSC-derived brain organoids | Cell Death Discovery BACE2 variant identified from HSCR patient causes AD-like phenotypes in hPSC-derived brain organoids | Cell Death Discovery](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41420-022-00845-5/MediaObjects/41420_2022_845_Fig5_HTML.png)
BACE2 variant identified from HSCR patient causes AD-like phenotypes in hPSC-derived brain organoids | Cell Death Discovery
![BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance](https://www.life-science-alliance.org/content/lsa/1/1/e201800026/F11.large.jpg)
BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance
![Schematic diagram of transcriptional regulation and function of the... | Download Scientific Diagram Schematic diagram of transcriptional regulation and function of the... | Download Scientific Diagram](https://www.researchgate.net/publication/7879983/figure/fig5/AS:280887540371460@1443980216352/Schematic-diagram-of-transcriptional-regulation-and-function-of-the-BACE2-and-BACE1-gene.png)
Schematic diagram of transcriptional regulation and function of the... | Download Scientific Diagram
![Schematic illustration of BACE1 and BACE2 structural organizations.... | Download Scientific Diagram Schematic illustration of BACE1 and BACE2 structural organizations.... | Download Scientific Diagram](https://www.researchgate.net/publication/316251802/figure/fig1/AS:484903209967616@1492621342483/Schematic-illustration-of-BACE1-and-BACE2-structural-organizations-Both-BACE1-and.png)
Schematic illustration of BACE1 and BACE2 structural organizations.... | Download Scientific Diagram
![The structure of the bACE2-Rm and the molecular basis of the bACE2-Rm... | Download Scientific Diagram The structure of the bACE2-Rm and the molecular basis of the bACE2-Rm... | Download Scientific Diagram](https://www.researchgate.net/publication/347922742/figure/fig2/AS:986078139936775@1612110757960/The-structure-of-the-bACE2-Rm-and-the-molecular-basis-of-the-bACE2-Rm-dimer-A-Overall.jpg)
The structure of the bACE2-Rm and the molecular basis of the bACE2-Rm... | Download Scientific Diagram
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BACE-2 Inhibitor | BACE 2 inhibitor | BACE2 Inhibitor 3l | BACE 2 Inhibitor 3l | BACE-2 Inhibitor 3l | CAS [1676107-08-6] | Axon 2957 | Axon Ligand™ with >99% purity available from stock from supplier Axon Medchem
![Processing of amyloid-protein precursor (APP) via the amyloidogenic or... | Download Scientific Diagram Processing of amyloid-protein precursor (APP) via the amyloidogenic or... | Download Scientific Diagram](https://www.researchgate.net/publication/365845867/figure/fig1/AS:11431281177720080@1690593751819/Processing-of-amyloid-protein-precursor-APP-via-the-amyloidogenic-or-non-amyloidogenic.png)
Processing of amyloid-protein precursor (APP) via the amyloidogenic or... | Download Scientific Diagram
![BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance](https://www.life-science-alliance.org/content/lsa/1/1/e201800026/F1.large.jpg)
BACE2 distribution in major brain cell types and identification of novel substrates | Life Science Alliance
![Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41598-019-45896-4/MediaObjects/41598_2019_45896_Fig1_HTML.png)
Common BACE2 Polymorphisms are Associated with Altered Risk for Alzheimer's Disease and CSF Amyloid Biomarkers in APOE ε4 Non-Carriers | Scientific Reports
Structure-Based Design of Selective β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2 | Journal of Medicinal Chemistry
![Design of potent and highly selective inhibitors for human β-secretase 2 (memapsin 1), a target for type 2 diabetes - Chemical Science (RSC Publishing) DOI:10.1039/C5SC03718B Design of potent and highly selective inhibitors for human β-secretase 2 (memapsin 1), a target for type 2 diabetes - Chemical Science (RSC Publishing) DOI:10.1039/C5SC03718B](https://pubs.rsc.org/image/article/2016/SC/c5sc03718b/c5sc03718b-f1_hi-res.gif)